Gcm1^tm1Hoso
Targeted Allele Detail

Summary

• Symbol: Gcm1^tm1Hoso
• Name: glial cells missing homolog 1; targeted mutation 1, Toshihiko Hosoya
• MGI ID: MGI:3653426
• Synonyms: Gcm1^tm1Hott
• Gene: Gcm1 Location: Chr9:77959240-77972906 bp, + strand Genetic Position: Chr9, 43.49 cM, cytoband E1-E3
• Alliance: Gcm1^tm1Hoso page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:109989
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding sequence for the GCM motif was replaced with an IRES, lacZ, and floxed neo cassette. Due to a frame shift, no beta-galactosidase activity is detected. (J:175891)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gcm1 Mutation: 23 strains or lines available

References

• Original: J:109989 Iwasaki Y, et al., The potential to induce glial differentiation is conserved between Drosophila and mammalian glial cells missing genes. Development. 2003 Dec;130(24):6027-35
• All: 2 reference(s)