Tg(Igk-V4CH27)1-2Shc
Transgene Detail

Summary

• Symbol: Tg(Igk-V4CH27)1-2Shc
• Name: transgene insertion 1-2, Stephen H Clarke
• MGI ID: MGI:3653438
• Synonyms: V4-Tg, Vk4-Tg
• Transgene: Tg(Igk-V4CH27)1-2Shc Location: unknown
• Alliance: Tg(Igk-V4CH27)1-2Shc page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Igk-V4CH27)1-2Shc expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Igk (MGI:96494)

• Mutation details: An 8.5 kb fragment derived from the PtC-specific lymphoma CH27 contained Vk4, Jk4, and Ck elements. This fragment was used to generate two founder lines. The 1-2 line has been characterized and contains 5-10 copies of the traqnsgene. (J:111246)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:111246 Arnold LW, et al., Development of B-1 cells: segregation of phosphatidyl choline-specific B cells to the B-1 population occurs after immunoglobulin gene expression. J Exp Med. 1994 May 1;179(5):1585-95
• All: 7 reference(s)