Gadd45g^tm1Mhol
Targeted Allele Detail

Summary

• Symbol: Gadd45g^tm1Mhol
• Name: growth arrest and DNA-damage-inducible 45 gamma; targeted mutation 1, M Christine Hollander
• MGI ID: MGI:3653832
• Gene: Gadd45g Location: Chr13:52000714-52002504 bp, + strand Genetic Position: Chr13, 26.36 cM, cytoband A5-B
• Alliance: Gadd45g^tm1Mhol page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110650
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A fragment of Gadd45g including exons 1-3 was replaced with a PMG-neo cassette. (J:199917)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gadd45g Mutation: 11 strains or lines available

References

• Original: J:110650 Cai Q, et al., Effects of expression of p53 and Gadd45 on osmotic tolerance of renal inner medullary cells. Am J Physiol Renal Physiol. 2006 Aug;291(2):F341-9
• All: 4 reference(s)