Rab3gap1^tm1Tkss
Targeted Allele Detail

Summary

• Symbol: Rab3gap1^tm1Tkss
• Name: RAB3 GTPase activating protein subunit 1; targeted mutation 1, Takuya Sasaki
• MGI ID: MGI:3654149
• Gene: Rab3gap1 Location: Chr1:127796510-127871605 bp, + strand Genetic Position: Chr1, 55.8 cM
• Alliance: Rab3gap1^tm1Tkss page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111069
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A targeting vector was designed to replace most of exon 1 and all of exon 2 with a neomycin resistance gene. (J:111069)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rab3gap1 Mutation: 38 strains or lines available

References

• Original: J:111069 Sakane A, et al., Rab3 GTPase-activating protein regulates synaptic transmission and plasticity through the inactivation of Rab3. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10029-34
• All: 1 reference(s)