Tg(tetO-Ipf1,EGFP)956.6Macd
Transgene Detail

Summary

• Symbol: Tg(tetO-Ipf1,EGFP)956.6Macd
• Name: transgene insertion 956-6, Raymond J MacDonald
• MGI ID: MGI:3655514
• Synonyms: Pdx1-EGFP, Pdx1-GFP, Pdx1^Tg, tetO-Pdx1, tetO-Pdx1-EGFP, tetO-Pdx1/EGFP, tetO/Pdx1/EGFP, Tg^Pdx1, tTA-responsive Pdx1-EGFP
• Transgene: Tg(tetO-Ipf1,EGFP)956.6Macd Location: unknown
• Alliance: Tg(tetO-Ipf1,EGFP)956.6Macd page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: A transgenic vector containing an Ipf1 minigene (both exons of Ipf1 linked by a shortened exon and preceded by a truncated 5' UTR and an IRES-linked EGFP reporter) under control of seven direct repeats of the tetracycline operator (tetO) fused to the human cytomegalovirus (hCMV) immediate early promoter. High expression of Ipf1 and EGFP is induced by the introduction of the tetracycline-transactivator protein by breeding with an appropriate mouse line. (J:79206)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:79206 Holland AM, et al., Experimental control of pancreatic development and maintenance. Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12236-41
• All: 4 reference(s)