Tg(Myh6-Sln)26Peri
Transgene Detail

Summary

• Symbol: Tg(Myh6-Sln)26Peri
• Name: transgene insertion 26, Muthu Periasamy
• MGI ID: MGI:3655879
• Synonyms: SLN TG
• Transgene: Tg(Myh6-Sln)26Peri Location: unknown
• Alliance: Tg(Myh6-Sln)26Peri page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Sln)26Peri expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Sln (MGI:1913652)

• Mutation details: This transgene consists of an N-terminal FLAG-tagged mouse Sln cDNA under the control of the mouse alpha-myosin heavy chain promoter, resulting in heart specific expression of Sln. Line 26 carries 2 copies of the transgene and expresses about 2-fold higher levels of Sln protein than line 20. (J:108309)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:108309 Babu GJ, et al., Targeted overexpression of sarcolipin in the mouse heart decreases sarcoplasmic reticulum calcium transport and cardiac contractility. J Biol Chem. 2006 Feb 17;281(7):3972-9
• All: 1 reference(s)