Gnpnat1^tm1Mak
Targeted Allele Detail

Summary

• Symbol: Gnpnat1^tm1Mak
• Name: glucosamine-phosphate N-acetyltransferase 1; targeted mutation 1, Tak Mak
• MGI ID: MGI:3662646
• Synonyms: Emeg32^-
• Gene: Gnpnat1 Location: Chr14:45613897-45626972 bp, - strand Genetic Position: Chr14, 22.92 cM
• Alliance: Gnpnat1^tm1Mak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111395
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace exons 1 and 2 with a neomycin resistance cassette. Western blot analysis demonstrated absence of protein in mutants. (J:111395)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gnpnat1 Mutation: 31 strains or lines available

References

• Original: J:111395 Boehmelt G, et al., Decreased UDP-GlcNAc levels abrogate proliferation control in EMeg32-deficient cells. EMBO J. 2000 Oct 2;19(19):5092-104
• All: 1 reference(s)