Ret^tm1.1Kln
Targeted Allele Detail

Summary

• Symbol: Ret^tm1.1Kln
• Name: ret proto-oncogene; targeted mutation 1.1, Rudiger Klein
• MGI ID: MGI:3662902
• Synonyms: Ret^-, Ret-null
• Gene: Ret Location: Chr6:118128706-118174679 bp, - strand Genetic Position: Chr6, 55.86 cM, cytoband E3-F1
• Alliance: Ret^tm1.1Kln page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110955
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Mice carrying the Ret^tm1Kln floxed allele were crossed to Deleter-Cre mice (Tg(Pgk1-cre)1Lni) to excise the floxed region and to generate heterozygous mice. (J:110955)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ret Mutation: 54 strains or lines available

References

• Original: J:110955 Kramer ER, et al., Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb. Neuron. 2006 Apr 6;50(1):35-47
• All: 4 reference(s)