Ccdc40^lnks
Chemically induced Allele Detail

Summary

• Symbol: Ccdc40^lnks
• Name: coiled-coil domain containing 40; links
• MGI ID: MGI:3662904
• Synonyms: Ccdc40^Q792X
• Gene: Ccdc40 Location: Chr11:119119398-119156064 bp, + strand Genetic Position: Chr11, 83.35 cM
• Alliance: Ccdc40^lnks page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a C-to-A change resulting in a nonsense mutation in the C-terminal coiled-coil domain. The amino acid substitution results in a stop codon in place of serine at position 792 (p.S792*). (J:168691)

Expression

In Mice Carrying this Mutation:	3 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccdc40 Mutation: 52 strains or lines available

References

• Original: J:168691 Becker-Heck A, et al., The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation. Nat Genet. 2011 Jan;43(1):79-84
• All: 4 reference(s)