Slc6a4^tm1(cre)Grch
Targeted Allele Detail

Summary

• Symbol: Slc6a4^tm1(cre)Grch
• Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; targeted mutation 1, Jay A Gingrich
• MGI ID: MGI:3663166
• Synonyms: htt-Cre
• Gene: Slc6a4 Location: Chr11:76889429-76923166 bp, + strand Genetic Position: Chr11, 46.18 cM
• Alliance: Slc6a4^tm1(cre)Grch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110958
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Slc6a4^tm1(cre)Grch expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Slc6a4 (MGI:96285)

• Mutation details: A cre recombinase gene was inserted into the gene. Under the control of this promoter, thalamic Cre expression was verified by in situ hybridization. (J:110958)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc6a4 (mouse) Summary of all recombinase alleles driven by Slc6a4. Alliance mouse Slc6a4 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc6a4 Mutation: 53 strains or lines available

References

• Original: J:110958 Weisstaub NV, et al., Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. Science. 2006 Jul 28;313(5786):536-40
• All: 1 reference(s)