Mafb^tm1Jeng
Targeted Allele Detail

Summary

• Symbol: Mafb^tm1Jeng
• Name: MAF bZIP transcription factor B; targeted mutation 1, James Douglas Engel
• MGI ID: MGI:3663168
• Synonyms: mafb^-, Mafb-GFP, Mafb^tm(GFP)UTR
• Gene: Mafb Location: Chr2:160205623-160208985 bp, - strand Genetic Position: Chr2, 80.92 cM
• Alliance: Mafb^tm1Jeng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111415
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a GFP into the locus. RT-PCR failed to detect transcript in mutants. (J:111415)

Expression

In Mice Carrying this Mutation:	84 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mafb Mutation: 20 strains or lines available

References

• Original: J:111415 Moriguchi T, et al., MafB is essential for renal development and F4/80 expression in macrophages. Mol Cell Biol. 2006 Aug;26(15):5715-27
• All: 32 reference(s)