Ptprg^tm1Shar
Targeted Allele Detail

Summary

• Symbol: Ptprg^tm1Shar
• Name: protein tyrosine phosphatase receptor type G; targeted mutation 1, Sheila Harroch
• MGI ID: MGI:3663183
• Synonyms: RPTPgamma^-
• Gene: Ptprg Location: Chr14:10227722-10916220 bp, - strand Genetic Position: Chr14, 6.33 cM, cytoband A2
• Alliance: Ptprg^tm1Shar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110322
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert an IRES-Betageo immediately downstream of exon 1. RT-PCR detected no transcript in mutant brains. (J:110322)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptprg Mutation: 116 strains or lines available

References

• Original: J:110322 Lamprianou S, et al., Receptor protein tyrosine phosphatase gamma is a marker for pyramidal cells and sensory neurons in the nervous system and is not necessary for normal development. Mol Cell Biol. 2006 Jul;26(13):5106-19
• All: 7 reference(s)