Map4k5^tm1Jhk
Targeted Allele Detail

Summary

• Symbol: Map4k5^tm1Jhk
• Name: mitogen-activated protein kinase kinase kinase kinase 5; targeted mutation 1, John H Kehrl
• MGI ID: MGI:3663310
• Gene: Map4k5 Location: Chr12:69850531-69939937 bp, - strand Genetic Position: Chr12, 28.94 cM, cytoband C3
• Alliance: Map4k5^tm1Jhk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112134
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A targeting vector was designed to replace exons 6 and 7 with a neomycin resistance cassette. (J:112134)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Map4k5 Mutation: 75 strains or lines available

References

• Original: J:112134 Shi CS, et al., The mitogen-activated protein kinase kinase kinase kinase GCKR positively regulates canonical and noncanonical Wnt signaling in B lymphocytes. Mol Cell Biol. 2006 Sep;26(17):6511-21
• All: 1 reference(s)