Card9^tm1Jrld
Targeted Allele Detail

Summary

• Symbol: Card9^tm1Jrld
• Name: caspase recruitment domain family, member 9; targeted mutation 1, Jurgen Ruland
• MGI ID: MGI:3663486
• Synonyms: Card9^-
• Gene: Card9 Location: Chr2:26242188-26250930 bp, - strand Genetic Position: Chr2, 18.87 cM
• Alliance: Card9^tm1Jrld page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111706
• Parent Cell Line: E14K (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1-4 were replaced with a neomycin resistance cassette. RT-PCR failed to detect transcript from mutants. (J:111706)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Card9 Mutation: 30 strains or lines available

References

• Original: J:111706 Gross O, et al., Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity. Nature. 2006 Aug 10;442(7103):651-6
• All: 28 reference(s)