Igk-Jtm1Cog
Targeted Allele Detail
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| Symbol: |
Igk-Jtm1Cog |
| Name: |
immunoglobulin kappa chain, joining region; targeted mutation 1, Michel Cogne |
| MGI ID: |
MGI:3663520 |
| Synonyms: |
kappaC |
| Gene: |
Igk-J Location: unknown Genetic Position: Chr6, Syntenic
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| Germline Transmission: |
Earliest citation of germline transmission:
J:110100
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| Parent Cell Line: |
E14 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Humanized sequence, Inserted expressed sequence) |
| Mutations: |
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Insertion, Intergenic deletion
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Mutation details: A vector was designed to replace the Jk cluster with floxed cassette containing a pVH promoter and the human VkJk containing 7 codons mutated from germline.
(J:110100)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Igk-J Mutation: |
11 strains or lines available
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| Original: |
J:110100 Sirac C, et al., Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7747-52 |
| All: |
2 reference(s) |
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Analysis Tools
