Capns1^tm2Pag
Targeted Allele Detail

Summary

• Symbol: Capns1^tm2Pag
• Name: calpain, small subunit 1; targeted mutation 1, Peter A Greer
• MGI ID: MGI:3663674
• Synonyms: Capn4^flox, Capn4^pz
• Gene: Capns1 Location: Chr7:29886361-29898236 bp, - strand Genetic Position: Chr7, 17.31 cM
• Alliance: Capns1^tm2Pag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110138
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was used to insert an IRES-lacZ-neo-loxP cassette into the 3' end of exon 11 and another loxP site into intron 8. (J:110138)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Capns1 Mutation: 34 strains or lines available

References

• Original: J:110138 Tan Y, et al., Conditional disruption of ubiquitous calpains in the mouse. Genesis. 2006 Jun;44(6):297-303
• All: 26 reference(s)