Fam184b^tm1Mnkm
Targeted Allele Detail

Summary

• Symbol: Fam184b^tm1Mnkm
• Name: family with sequence similarity 184, member B; targeted mutation 1, Manabu Nakayama
• MGI ID: MGI:3663687
• Synonyms: KIAA1276^-
• Gene: Fam184b Location: Chr5:45687047-45796843 bp, - strand Genetic Position: Chr5, 25.04 cM, cytoband B3
• Alliance: Fam184b^tm1Mnkm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111319
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A sequence of 757 bp was deleted, including part of exon 2. Northern blot and RT-PCR of failed to detect intact transcript in mutants. (J:111319)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fam184b Mutation: 46 strains or lines available

References

• Original: J:111319 Nakayama M, et al., A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins. FASEB J. 2006 Aug;20(10):1718-20
• All: 1 reference(s)