Cytip^tm1Tes
Targeted Allele Detail

Summary

• Symbol: Cytip^tm1Tes
• Name: cytohesin 1 interacting protein; targeted mutation 1, Lino Tessarollo
• MGI ID: MGI:3664082
• Synonyms: Cybr^-
• Gene: Cytip Location: Chr2:58019149-58085544 bp, - strand Genetic Position: Chr2, 33.05 cM
• Alliance: Cytip^tm1Tes page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110320
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 1 was removed via cre-mediated recombination. Western blot analysis failed to detect protein in mutant splenocytes. (J:110320)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cytip Mutation: 24 strains or lines available

References

• Original: J:110320 Coppola V, et al., The scaffold protein cybr is required for cytokine-modulated trafficking of leukocytes in vivo. Mol Cell Biol. 2006 Jul;26(14):5249-58
• All: 2 reference(s)