Ncoa1^tm1Hkaw
Targeted Allele Detail

Summary

• Symbol: Ncoa1^tm1Hkaw
• Name: nuclear receptor coactivator 1; targeted mutation 1, Hiroshi Kawaguchi
• MGI ID: MGI:3664106
• Synonyms: SRC-1^L3
• Gene: Ncoa1 Location: Chr12:4297362-4527182 bp, - strand Genetic Position: Chr12, 2.05 cM, cytoband A2-A3
• Alliance: Ncoa1^tm1Hkaw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111490
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exon 4, including a neomycin resistance gene within the floxed sequence. (J:111490)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ncoa1 Mutation: 169 strains or lines available

References

• Original: J:111490 Yamada T, et al., SRC-1 is necessary for skeletal responses to sex hormones in both males and females. J Bone Miner Res. 2004 Sep;19(9):1452-61
• All: 3 reference(s)