Gmnn^{Gt(XT0615)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Gmnn^{Gt(XT0615)Wtsi}
• Name: geminin; gene trap XT0615, Wellcome Trust Sanger Institute
• MGI ID: MGI:3664114
• Synonyms: Gmnn^GT, Gmnn^{Gt(betageo)Wtsi}
• Gene: Gmnn Location: Chr13:24935828-24945906 bp, - strand Genetic Position: Chr13, 10.64 cM
• Alliance: Gmnn^{Gt(XT0615)Wtsi} page

Mutation origin

• Mutant Cell Line: XT0615
• Germline Transmission: Earliest citation of germline transmission: J:110696
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxf
• A gene trap vector containing a beta-geo inserted into intron 1 of the locus. (J:110696)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XT0615	CG870133 ; (MGI Seq Detail)	5' RACE	Chr13:24945795-24945921 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  16 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	15 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gmnn Mutation: 27 strains or lines available

References

• Original: J:110696 Gonzalez MA, et al., Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development. Genes Dev. 2006 Jul 15;20(14):1880-4
• All: 1 reference(s)