Tulp3^hhkr
Chemically induced Allele Detail

Summary

• Symbol: Tulp3^hhkr
• Name: TUB like protein 3; hitchhiker
• MGI ID: MGI:3664273
• Synonyms: RECB4
• Gene: Tulp3 Location: Chr6:128298124-128332814 bp, - strand Genetic Position: Chr6, 62.96 cM
• Alliance: Tulp3^hhkr page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation, identified in an ENU mutagenesis screen, alters a splice site and results in deletion of exon 2 from the transcript. (J:147584)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tulp3 Mutation: 54 strains or lines available

References

• Original: J:147584 Patterson VL, et al., Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway. Hum Mol Genet. 2009 May 15;18(10):1719-39
• All: 2 reference(s)