Tg(Myh6-Hoxb7)25Ssp
Transgene Detail

Summary

• Symbol: Tg(Myh6-Hoxb7)25Ssp
• Name: transgene insertion 25, S Steven Potter
• MGI ID: MGI:3664274
• Synonyms: alpha-MHC-Hoxb-7
• Transgene: Tg(Myh6-Hoxb7)25Ssp Location: unknown
• Alliance: Tg(Myh6-Hoxb7)25Ssp page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Hoxb7)25Ssp expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Hoxb7 (MGI:96188)

• Mutation details: This transgene consists of both exons of Hoxb7 under the control of the alpha-myosin heavy chain promoter, driving the expression of Hoxb7 in the heart. Whole mount in situ hybridization shows ectopic expression of Hoxb7 in the heart, both in the atrium and ventricle. (J:28713)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:28713 Argao EA, et al., Malformations of the heart, kidney, palate, and skeleton in alpha-MHC-Hoxb-7 transgenic mice. Mech Dev. 1995 Aug;52(2-3):291-303
• All: 1 reference(s)