Tg(KLK3-cre)1Ches
Transgene Detail

Summary

• Symbol: Tg(KLK3-cre)1Ches
• Name: transgene insertion 1, Nicholas Chester
• MGI ID: MGI:3664341
• Synonyms: PSA-cre
• Transgene: Tg(KLK3-cre)1Ches Location: unknown
• Alliance: Tg(KLK3-cre)1Ches page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(KLK3-cre)1Ches expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  KLK3 (354)

  Klk1	(MGI:102850)
  Klk1b1	(MGI:892019)
  Klk1b3	(MGI:97322)
  Klk1b4	(MGI:97320)
  Klk1b5	(MGI:892020)
  Klk1b8	(MGI:892018)
  Klk1b9	(MGI:95293)
  Klk1b11	(MGI:892023)
  Klk1b16	(MGI:891982)
  Klk1b21	(MGI:892022)
  Klk1b22	(MGI:95291)
  Klk1b24	(MGI:892021)
  Klk1b26	(MGI:891981)
  Klk1b27	(MGI:891980)

• Mutation details: A transgenic construct was made with the cre transgene under control of a 6kb fragment of the human KLK3 (PSA) gene. This transgenic mouse line exhibited poor and variable cre expression in the prostate gland. The line no longer exists. (J:112115)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	KLK3 (human) Summary of all recombinase alleles driven by KLK3. Alliance human KLK3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:112115 Chester N, et al., Mutation of the murine Bloom's syndrome gene produces global genome destabilization. Mol Cell Biol. 2006 Sep;26(17):6713-26
• All: 1 reference(s)