Mapk9^tm1.1Rjd
Targeted Allele Detail

Summary

• Symbol: Mapk9^tm1.1Rjd
• Name: mitogen-activated protein kinase 9; targeted mutation 1.1, Roger J Davis
• MGI ID: MGI:3664582
• Synonyms: Jnk2^M108G, Jnk2^MG
• Gene: Mapk9 Location: Chr11:49737578-49777248 bp, + strand Genetic Position: Chr11, 29.96 cM, cytoband B1.2
• Alliance: Mapk9^tm1.1Rjd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112737
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: Codon 108 was changed from a methionine to a glycine (M108G) in exon 6. A floxed neo was removed via cre mediated recombination. (J:112737)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Mapk9 Mutation: 33 strains or lines available

References

• Original: J:112737 Jaeschke A, et al., JNK2 is a positive regulator of the cJun transcription factor. Mol Cell. 2006 Sep 15;23(6):899-911
• All: 4 reference(s)