Tbx21^tm1Srnr
Targeted Allele Detail

Summary

• Symbol: Tbx21^tm1Srnr
• Name: T-box 21; targeted mutation 1, Steven L Reiner
• MGI ID: MGI:3664621
• Synonyms: T-bet^-, T-bet KO, Tbx21^-
• Gene: Tbx21 Location: Chr11:96988897-97006157 bp, - strand Genetic Position: Chr11, 60.95 cM, cytoband D
• Alliance: Tbx21^tm1Srnr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112679
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 2-6 were deleted. (J:112679)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx21 Mutation: 39 strains or lines available

References

• Original: J:112679 Intlekofer AM, et al., Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat Immunol. 2005 Dec;6(12):1236-44
• All: 15 reference(s)