Git2^tm1Hsb
Targeted Allele Detail

Summary

• Symbol: Git2^tm1Hsb
• Name: GIT ArfGAP 2; targeted mutation 1, Hisataka Sabe
• MGI ID: MGI:3664625
• Synonyms: Git2^-
• Gene: Git2 Location: Chr5:114865469-114912647 bp, - strand Genetic Position: Chr5, 55.99 cM
• Alliance: Git2^tm1Hsb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112663
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neo was inserted into exon 2 of the locus. This exon contains the ATG. (J:112663)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Git2 Mutation: 78 strains or lines available

References

• Original: J:112663 Mazaki Y, et al., Neutrophil direction sensing and superoxide production linked by the GTPase-activating protein GIT2. Nat Immunol. 2006 Jul;7(7):724-31
• All: 3 reference(s)