Arpc3^tm1Jtak
Targeted Allele Detail

Summary

• Symbol: Arpc3^tm1Jtak
• Name: actin related protein 2/3 complex, subunit 3; targeted mutation 1, Junji Takeda
• MGI ID: MGI:3664649
• Synonyms: Arpc3^KO
• Gene: Arpc3 Location: Chr5:122529941-122544244 bp, + strand Genetic Position: Chr5, 62.34 cM
• Alliance: Arpc3^tm1Jtak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111402
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 2 was replaced with a PGK-neo selection cassette via homologous recombination. (J:111402)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Arpc3 Mutation: 12 strains or lines available

References

• Original: J:111402 Yae K, et al., Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth. Mol Cell Biol. 2006 Aug;26(16):6185-96
• All: 1 reference(s)