Pdia3^tm1.1Gjh
Targeted Allele Detail

Summary

• Symbol: Pdia3^tm1.1Gjh
• Name: protein disulfide isomerase associated 3; targeted mutation 1.1, Gunter J Hammerling
• MGI ID: MGI:3664743
• Synonyms: B-Erp57^-
• Gene: Pdia3 Location: Chr2:121244383-121269168 bp, + strand Genetic Position: Chr2, 60.38 cM
• Alliance: Pdia3^tm1.1Gjh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112606
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Cre mediated recombination resulted in the deletion of exons 2 and 3. (J:112606)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdia3 Mutation: 38 strains or lines available

References

• Original: J:112606 Garbi N, et al., Impaired assembly of the major histocompatibility complex class I peptide-loading complex in mice deficient in the oxidoreductase ERp57. Nat Immunol. 2006 Jan;7(1):93-102
• All: 1 reference(s)