Myh10^tm4Rsad
Targeted Allele Detail

Summary

• Symbol: Myh10^tm4Rsad
• Name: myosin, heavy polypeptide 10, non-muscle; targeted mutation 4, Robert S Adelstein
• MGI ID: MGI:3664764
• Synonyms: B^deltaB1N
• Gene: Myh10 Location: Chr11:68582385-68707458 bp, + strand Genetic Position: Chr11, 41.95 cM, cytoband B3
• Alliance: Myh10^tm4Rsad page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112536
• Parent Cell Line: CMT-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon B1 was replaced by a floxed neo cassette. (J:112536)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Myh10 Mutation: 95 strains or lines available

References

• Original: J:112536 Ma X, et al., Function of the neuron-specific alternatively spliced isoforms of nonmuscle myosin II-B during mouse brain development. Mol Biol Cell. 2006 May;17(5):2138-49
• All: 2 reference(s)