Sfrp2^tm1Sato
Targeted Allele Detail

Summary

• Symbol: Sfrp2^tm1Sato
• Name: secreted frizzled-related protein 2; targeted mutation 1, Thomas N Sato
• MGI ID: MGI:3664776
• Synonyms: sFRP2^lacZ
• Gene: Sfrp2 Location: Chr3:83673628-83681621 bp, + strand Genetic Position: Chr3, 37.37 cM
• Alliance: Sfrp2^tm1Sato page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112802
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first coding exon was replaced with lacZ via homologous recombination. The selection cassette was removed by crossing mice to germline Cre expressing mice. (J:112802)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sfrp2 Mutation: 30 strains or lines available

References

• Original: J:112802 Lei Q, et al., Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube. Dev Cell. 2006 Sep;11(3):325-37
• All: 4 reference(s)