Myo1f^tm1.1Flv
Targeted Allele Detail

Summary

• Symbol: Myo1f^tm1.1Flv
• Name: myosin IF; targeted mutation 1.1, Richard A Flavell
• MGI ID: MGI:3664779
• Gene: Myo1f Location: Chr17:33774681-33826738 bp, + strand Genetic Position: Chr17, 17.98 cM, cytoband B-C
• Alliance: Myo1f^tm1.1Flv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:113020
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 5 and 6 were deleted from the locus via cre mediated recombination. Absense of protein was confirmed by Western blot analysis. (J:113020)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Myo1f Mutation: 66 strains or lines available

References

• Original: J:113020 Kim SV, et al., Modulation of cell adhesion and motility in the immune system by Myo1f. Science. 2006 Oct 6;314(5796):136-9
• All: 4 reference(s)