Gria2^tm3.1Rsp
Targeted Allele Detail

Summary

• Symbol: Gria2^tm3.1Rsp
• Name: glutamate receptor, ionotropic, AMPA2 (alpha 2); targeted mutation 3.1, Rolf Sprengel
• MGI ID: MGI:3665137
• Gene: Gria2 Location: Chr3:80588757-80710142 bp, - strand Genetic Position: Chr3, 35.5 cM
• Alliance: Gria2^tm3.1Rsp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111689
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele is a derivative of Gria2^tm3Rsp in which the loxP flanked exon 11 is removed in the germline by crossing mice carrying this allele to mice carrying the Tg(CMV-Cre)1Cgn transgene. (J:111689)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gria2 Mutation: 79 strains or lines available

References

• Original: J:111689 Shimshek DR, et al., Forebrain-specific glutamate receptor B deletion impairs spatial memory but not hippocampal field long-term potentiation. J Neurosci. 2006 Aug 16;26(33):8428-40
• All: 3 reference(s)