Aldh1a2^tm2Soc
Targeted Allele Detail

Summary

• Symbol: Aldh1a2^tm2Soc
• Name: aldehyde dehydrogenase family 1, subfamily A2; targeted mutation 2, Shanthini Sockanathan
• MGI ID: MGI:3665181
• Synonyms: Raldh2^lox
• Gene: Aldh1a2 Location: Chr9:71123071-71203525 bp, + strand Genetic Position: Chr9, 39.85 cM
• Alliance: Aldh1a2^tm2Soc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112635
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted 5' of exon 4 and an inversely oriented tk-neo cassette followed by a second loxP site were inserted 3' of exon 4. (J:112635)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aldh1a2 Mutation: 38 strains or lines available

References

• Original: J:112635 Ji SJ, et al., Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons. Dev Biol. 2006 Sep 1;297(1):249-61
• All: 2 reference(s)