Ptger4^tm1.2Matb
Targeted Allele Detail

Summary

• Symbol: Ptger4^tm1.2Matb
• Name: prostaglandin E receptor 4 (subtype EP4); targeted mutation 2, Matthew D Breyer
• MGI ID: MGI:3665234
• Synonyms: EP4^del
• Gene: Ptger4 Location: Chr15:5262880-5273668 bp, - strand Genetic Position: Chr15, 1.99 cM
• Alliance: Ptger4^tm1.2Matb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:92301
• Parent Cell Line: TL1/TL-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Deletion of exon 2 was accomplished by taking single cell embryos carrrying an allele containing loxP sites that flank exon 2 and injecting a cre-expression plasmid. Mice were produced from the embryos that carried the deleted allele. (J:92301)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptger4 Mutation: 33 strains or lines available

References

• Original: J:92301 Schneider A, et al., Generation of a conditional allele of the mouse prostaglandin EP(4) receptor. Genesis. 2004 Sep;40(1):7-14
• All: 5 reference(s)