Ifngtm1Lky
Targeted Allele Detail
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Symbol: |
Ifngtm1Lky |
Name: |
interferon gamma; targeted mutation 1, Richard M Locksley |
MGI ID: |
MGI:3665254 |
Synonyms: |
Yeti |
Gene: |
Ifng Location: Chr10:118276951-118281797 bp, + strand Genetic Position: Chr10, 66.75 cM
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Alliance: |
Ifngtm1Lky page
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Allele Type: |
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Targeted (Reporter) |
Mutation: |
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Insertion
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Mutation details: An IRES element, eYFP and a bovine polyA sequence followed by a floxed neomycin resistance cassette were inserted into the end of the coding sequence. Targeting took place in ES cells homozygous for Tg(Prm-cre)70Og, which express Cre recombinase in male germ cells. Cre-mediated excision subsequently removed the neomycin cassette upon transmission from male chimeric mice. The protamine-cre transgene was separated from the knock-in allele by crossing germline male mutant mice with C57BL/6 or BALB/c mice.
(J:113265)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ifng Mutation: |
47 strains or lines available
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Original: |
J:113265 Stetson DB, et al., Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J Exp Med. 2003 Oct 6;198(7):1069-76 |
All: |
32 reference(s) |
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