Trdc^tm1Mal
Targeted Allele Detail

Summary

• Symbol: Trdc^tm1Mal
• Name: T cell receptor delta, constant region; targeted mutation 1, Bernard Malissen
• MGI ID: MGI:3665255
• Synonyms: TcrdH2BeGFP, Tcrd-H2BEGFP, Trdc^tm1Mal
• Gene: Trdc Location: Chr14:54380308-54383565 bp, + strand Genetic Position: Chr14, 27.66 cM
• Alliance: Trdc^tm1Mal page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112658
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: An expression cassette encoding an internal ribosomal entry site (IRES) and a fusion of human histone H2B and enhanced green fluorescence protein (EGFP) was inserted in the 3' untranslated region. (J:112658)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Trdc Mutation: 7 strains or lines available

References

• Original: J:112658 Prinz I, et al., Visualization of the earliest steps of gammadelta T cell development in the adult thymus. Nat Immunol. 2006 Sep;7(9):995-1003
• All: 34 reference(s)