Fen1^tm1Bew
Targeted Allele Detail

Summary

• Symbol: Fen1^tm1Bew
• Name: flap structure specific endonuclease 1; targeted mutation 1, Be Wieringa
• MGI ID: MGI:3665273
• Synonyms: Fen1^-
• Gene: Fen1 Location: Chr19:10176496-10181533 bp, - strand Genetic Position: Chr19, 6.54 cM
• Alliance: Fen1^tm1Bew page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112968
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Exon 2 was interrupted by the insertion of a neomycin resistance gene. (J:112968)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fen1 Mutation: 32 strains or lines available

References

• Original: J:112968 van den Broek WJ, et al., Fen1 does not control somatic hypermutability of the (CTG)(n)*(CAG)(n) repeat in a knock-in mouse model for DM1. FEBS Lett. 2006 Oct 2;580(22):5208-14
• All: 1 reference(s)