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Fen1tm1Bew
Targeted Allele Detail
Summary
Symbol: Fen1tm1Bew
Name: flap structure specific endonuclease 1; targeted mutation 1, Be Wieringa
MGI ID: MGI:3665273
Synonyms: Fen1-
Gene: Fen1  Location: Chr19:10176496-10181533 bp, - strand  Genetic Position: Chr19, 6.54 cM
Alliance: Fen1tm1Bew page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112968
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Exon 2 was interrupted by the insertion of a neomycin resistance gene. (J:112968)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fen1 Mutation:  32 strains or lines available
References
Original:  J:112968 van den Broek WJ, et al., Fen1 does not control somatic hypermutability of the (CTG)(n)*(CAG)(n) repeat in a knock-in mouse model for DM1. FEBS Lett. 2006 Oct 2;580(22):5208-14
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory