Pla2g15^tm1Jash
Targeted Allele Detail

Summary

• Symbol: Pla2g15^tm1Jash
• Name: phospholipase A2, group XV; targeted mutation 1, James A Shayman
• MGI ID: MGI:3665282
• Gene: Pla2g15 Location: Chr8:106877031-106891347 bp, + strand Genetic Position: Chr8, 53.1 cM
• Alliance: Pla2g15^tm1Jash page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111561
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 5 was flanked by loxP sites. A PGK-neo flanked by FRT sites was included in the vector and subsequently removed by crossing with mice expressing flp recombinase in the germline. (J:111561)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pla2g15 Mutation: 30 strains or lines available

References

• Original: J:111561 Hiraoka M, et al., Lysosomal phospholipase A2 and phospholipidosis. Mol Cell Biol. 2006 Aug;26(16):6139-48
• All: 1 reference(s)