Gabpa^tm1.1Sjb
Targeted Allele Detail

Summary

• Symbol: Gabpa^tm1.1Sjb
• Name: GA repeat binding protein, alpha; targeted mutation 1.1, Steven J Burden
• MGI ID: MGI:3665313
• Synonyms: Gabpalpha^-
• Gene: Gabpa Location: Chr16:84631813-84660667 bp, + strand Genetic Position: Chr16, 46.92 cM, cytoband C3-4
• Alliance: Gabpa^tm1.1Sjb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121823
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Deletion of exons 8 and 9, which encode the DNA-binding region, was accomplished by mating mice contining loxP sites in introns 7 and 9 to CMV-Cre mice. Resulting progeny carried a deletion of the sequences flanked by the loxP sites. (J:121823)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gabpa Mutation: 67 strains or lines available

References

• Original: J:121823 Jaworski A, et al., GA-Binding Protein Is Dispensable for Neuromuscular Synapse Formation and Synapse-Specific Gene Expression. Mol Cell Biol. 2007 Jul;27(13):5040-6
• All: 3 reference(s)