Tcra-Jtm1Kgwa
Targeted Allele Detail
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| Symbol: |
Tcra-Jtm1Kgwa |
| Name: |
T cell receptor alpha, joining region; targeted mutation 1, Osami Kanagawa |
| MGI ID: |
MGI:3665411 |
| Synonyms: |
2B4alphKI |
| Gene: |
Tcra-J Location: unknown Genetic Position: Chr14, Syntenic
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| Germline Transmission: |
Earliest citation of germline transmission:
J:50143
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| Parent Cell Line: |
E14 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: A PGK-neo and a rearranged 2B4 TCR ValphaJalpha and Ig heavy chain enhancer (2B4-alpha IgHepsilon) to replace the J47-J50 region of the locus.
(J:50143)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Tcra-J Mutation: |
0 strains or lines available
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| Original: |
J:50143 Wang F, et al., Rapid deletion of rearranged T cell antigen receptor (TCR) Valpha-Jalpha segment by secondary rearrangement in the thymus: role of continuous rearrangement of TCR alpha chain gene and positive selection in the T cell repertoire formation. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11834-9 |
| All: |
3 reference(s) |
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Analysis Tools
