Sez6^tm1Hta
Targeted Allele Detail

Summary

• Symbol: Sez6^tm1Hta
• Name: seizure related gene 6; targeted mutation 1, Hiroshi Takeshima
• MGI ID: MGI:3665421
• Synonyms: Bsrp-C KO
• Gene: Sez6 Location: Chr11:77821626-77869874 bp, + strand Genetic Position: Chr11, 46.74 cM
• Alliance: Sez6^tm1Hta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111556
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced exons 2 and 3. Absence of transcript and protein were confirmed by Northern and Western blot, respectively. (J:111556)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sez6 Mutation: 72 strains or lines available

References

• Original: J:111556 Miyazaki T, et al., Disturbance of cerebellar synaptic maturation in mutant mice lacking BSRPs, a novel brain-specific receptor-like protein family. FEBS Lett. 2006 Jul 24;580(17):4057-64
• All: 1 reference(s)