Fgr^Mhdaali18
Chemically induced Allele Detail

Summary

• Symbol: Fgr^Mhdaali18
• Name: FGR proto-oncogene, Src family tyrosine kinase; Abnormal limb
• MGI ID: MGI:3665439
• Synonyms: Ali18
• Gene: Fgr Location: Chr4:132701406-132729204 bp, + strand Genetic Position: Chr4, 66.11 cM
• Alliance: Fgr^Mhdaali18 page

Morphologic appearance of feet and tail of Fgr^Mhdaali18/Fgr^Mhdaali18 and Fgr^Mhdaali18/Fgr^Mhdaali18+ mice.

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• ENU-mutagenesis induced a missense mutation in the C-terminal regulatory tail region. (J:266810)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgr Mutation: 132 strains or lines available

References

• Original: J:112868 Abe K, et al., New ENU-induced semidominant mutation, Ali18, causes inflammatory arthritis, dermatitis, and osteoporosis in the mouse. Mamm Genome. 2006 Sep;17(9):915-26
• All: 5 reference(s)