Tg(Shh)#Dje
Transgene Detail

Summary

• Symbol: Tg(Shh)#Dje
• Name: transgene insertion #, Douglas J Epstein
• MGI ID: MGI:3665473
• Synonyms: Shh-P1
• Transgene: Tg(Shh)#Dje Location: unknown
• Alliance: Tg(Shh)#Dje page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Shh)#Dje expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Shh (MGI:98297)

• Mutation details: The transgene was constructed using P1 5527, a 100 kb P1 bacteriophage library clone that overlapped the Shh open reading frame, extending ~10 Kb upstream and ~90 kb downstream from the translational start site. Two independent lines, each carrying 4-6 copies of the transgene and displaying similar phenotypes were created. (J:79100)

Expression

In Structures Affected by this Mutation:

10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:79100 Riccomagno MM, et al., Specification of the mammalian cochlea is dependent on Sonic hedgehog. Genes Dev. 2002 Sep 15;16(18):2365-78
• All: 6 reference(s)