Tg(HIST1H2BB/EGFP)1Pa
Transgene Detail

Summary

• Symbol: Tg(HIST1H2BB/EGFP)1Pa
• Name: transgene insertion 1, Virginia E Papaioannou
• MGI ID: MGI:3686857
• Synonyms: CAG::H2B-EGFP, H2B-EGFP, H2B-GFPtg, HBb-EGFP
• Transgene: Tg(HIST1H2BB/EGFP)1Pa Location: unknown
• Alliance: Tg(HIST1H2BB/EGFP)1Pa page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:109836
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The coding sequence of EGFP was placed C-terminally to the coding sequence of the human histone H2B gene. When placed under control of the chicken beta actin promoter/enhancer coupled with the cytomegalovirus (CMV) immediate-early enhancer/promoter, a fluorescent fusion protein (H2B-EGFP) is produced. (J:109836)

Tumor Data

List all tumor models in MMHCdb carrying Tg(HIST1H2BB/EGFP)1Pa

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:109836 Hadjantonakis AK, et al., Dynamic in vivo imaging and cell tracking using a histone fluorescent protein fusion in mice. BMC Biotechnol. 2004 Dec 24;4:33
• All: 44 reference(s)