Il4^tm1(CD2)Mmrs
Targeted Allele Detail

Summary

• Symbol: Il4^tm1(CD2)Mmrs
• Name: interleukin 4; targeted mutation 1, Markus Mohrs
• MGI ID: MGI:3686902
• Synonyms: IL4^KN2, KN2
• Gene: Il4 Location: Chr11:53503287-53509492 bp, - strand Genetic Position: Chr11, 31.97 cM
• Alliance: Il4^tm1(CD2)Mmrs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:113279
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• The first two exons were replaced with human CD2. (J:113279)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il4 Mutation: 46 strains or lines available

References

• Original: J:113279 Mohrs K, et al., A two-step process for cytokine production revealed by IL-4 dual-reporter mice. Immunity. 2005 Oct;23(4):419-29
• All: 38 reference(s)