Arid4b^tm1Alb
Targeted Allele Detail

Summary

• Symbol: Arid4b^tm1Alb
• Name: AT-rich interaction domain 4B; targeted mutation 1, Arthur L Beaudet
• MGI ID: MGI:3687005
• Synonyms: Arid4b^-
• Gene: Arid4b Location: Chr13:14238334-14374188 bp, + strand Genetic Position: Chr13, 5.29 cM
• Alliance: Arid4b^tm1Alb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:113402
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A vector was designed to replace exon 1 with a floxed neo cassette. (J:113402)

Disease models

Expression

In Mice Carrying this Mutation:	29 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arid4b Mutation: 67 strains or lines available

References

• Original: J:113402 Wu MY, et al., Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain. Genes Dev. 2006 Oct 15;20(20):2859-70
• All: 4 reference(s)