Serpinb9^tm1Arp
Targeted Allele Detail

Summary

• Symbol: Serpinb9^tm1Arp
• Name: serine (or cysteine) peptidase inhibitor, clade B, member 9; targeted mutation 1, Philip G Ashton-Rickardt
• MGI ID: MGI:3687210
• Synonyms: M Spi6 delta Neo, Spi6^-
• Gene: Serpinb9 Location: Chr13:33187233-33201940 bp, + strand Genetic Position: Chr13, 13.79 cM
• Alliance: Serpinb9^tm1Arp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:113349
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 7 was replaced with a floxed neomycin resistance cassette that was subsequently removed. (J:113349)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Serpinb9 Mutation: 34 strains or lines available

References

• Original: J:113349 Zhang M, et al., Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules. Immunity. 2006 Apr;24(4):451-61
• All: 8 reference(s)