Rag2^tm1Tgi
Targeted Allele Detail

Summary

• Symbol: Rag2^tm1Tgi
• Name: recombination activating gene 2; targeted mutation 1, Masaru Taniguchi
• MGI ID: MGI:3687306
• Synonyms: Rag2:GFP
• Gene: Rag2 Location: Chr2:101455063-101462874 bp, + strand Genetic Position: Chr2, 53.87 cM
• Alliance: Rag2^tm1Tgi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:113641
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The locus was interrupted by the insertion of a floxed GFP-neo cassette. GFP was expressed in the appropriate stages of developing T and B cells. (J:113641)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rag2 Mutation: 119 strains or lines available

References

• Original: J:113641 Kondo E, et al., Expression of recombination-activating gene in mature peripheral T cells in Peyer's patch. Int Immunol. 2003 Mar;15(3):393-402
• All: 3 reference(s)