Ptch1^tm1.1Yy
Targeted Allele Detail

Summary

• Symbol: Ptch1^tm1.1Yy
• Name: patched 1; targeted mutation 1.1, Yingzi Yang
• MGI ID: MGI:3687453
• Synonyms: Ptch1^deltaloxP
• Gene: Ptch1 Location: Chr13:63656142-63721274 bp, - strand Genetic Position: Chr13, 32.8 cM
• Alliance: Ptch1^tm1.1Yy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112462
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 1 and 2 were removed via cre mediated recombination. (J:112462)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptch1 Mutation: 115 strains or lines available

References

• Original: J:112462 Mak KK, et al., Wnt/{beta}-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation. Development. 2006 Sep;133(18):3695-707
• All: 3 reference(s)