Tg(KRT14-Edn3)1Takk
Transgene Detail

Summary

• Symbol: Tg(KRT14-Edn3)1Takk
• Name: transgene insertion 1, Takahiro Kusinada
• MGI ID: MGI:3687548
• Synonyms: ET3^Tg/+, Tg(KRT14-Edn3)
• Transgene: Tg(KRT14-Edn3)1Takk Location: unknown
• Alliance: Tg(KRT14-Edn3)1Takk page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-Edn3)1Takk expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Edn3 (MGI:95285)

• Mutation details: The transgene comprises a cDNA encoding mouse endothelin 3 inserted into an expression cassette containing upstream genomic sequences from the human keratin 14 gene, a rabbit beta-globin intron, and the polyadenylation signal of the human keratin gene. (J:100658, J:104881)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:100658 Kurita K, et al., Suppression of progressive loss of coat color in microphthalmia-vitiligo mutant mice. J Invest Dermatol. 2005 Sep;125(3):538-44
• All: 2 reference(s)